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Thoralf Lange Selected Research

ribonucleotide polymerase

9/2009A co-operative evaluation of different methods of detecting BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on second-line dasatinib or nilotinib therapy after failure of imatinib.
9/2005High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy.

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Thoralf Lange Research Topics

Disease

20BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2020 - 03/2003
10Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/2019 - 01/2006
8Leukemia
02/2019 - 11/2005
7Multiple Myeloma
01/2019 - 04/2007
5Neoplasms (Cancer)
01/2020 - 05/2007
4Philadelphia Chromosome
09/2014 - 12/2005
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2011 - 01/2004
3Graft vs Host Disease (Graft-Versus-Host Disease)
10/2014 - 03/2007
3Hematologic Neoplasms (Hematological Malignancy)
01/2011 - 09/2007
3Blast Crisis (Blast Phase)
04/2006 - 03/2003
2Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
10/2019 - 09/2013
2Pathologic Complete Response
01/2019 - 04/2017
2Colorectal Neoplasms (Colorectal Cancer)
01/2018 - 10/2015
2Residual Neoplasm
04/2017 - 08/2011
2Primary Myelofibrosis (Myelosclerosis)
11/2015 - 04/2010
2Non-Hodgkin Lymphoma (Lymphosarcoma)
09/2010 - 01/2008
2Mycoses (Diseases, Fungus)
08/2010 - 04/2010
2Infections
04/2009 - 08/2006
1Wilms Tumor (Wilm's Tumor)
02/2019
1Disease Progression
10/2015
1Sarcoma (Soft Tissue Sarcoma)
09/2013
1Chromosome Aberrations (Chromosome Abnormalities)
05/2013
1Genomic Instability
05/2013
1Aplastic Anemia (Anemia, Hypoplastic)
10/2009
1Renal Cell Carcinoma (Grawitz Tumor)
10/2009
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
11/2008
1Burkitt Lymphoma (Burkitt's Lymphoma)
11/2008
1Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
02/2008
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
02/2008
1Myeloproliferative Disorders (Myeloproliferative Disorder)
02/2008
1Parotitis (Parotiditis)
08/2006
1Bronchiolitis Obliterans Syndrome
04/2006
1Hematologic Diseases (Blood Diseases)
02/2003

Drug/Important Bio-Agent (IBA)

16Imatinib Mesylate (Gleevec)FDA Link
12/2020 - 03/2003
8Phosphotransferases (Kinase)IBA
09/2014 - 01/2004
7fludarabineIBA
01/2019 - 02/2003
4Complementary DNA (cDNA)IBA
01/2020 - 09/2005
4Tyrosine Kinase InhibitorsIBA
04/2018 - 08/2011
4Bendamustine HydrochlorideFDA Link
12/2017 - 07/2013
3nilotinibFDA Link
04/2018 - 09/2009
3Biomarkers (Surrogate Marker)IBA
04/2018 - 09/2013
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
10/2014 - 02/2003
3Pharmaceutical PreparationsIBA
10/2009 - 01/2004
2DNA (Deoxyribonucleic Acid)IBA
10/2019 - 09/2013
2Bevacizumab (Avastin)FDA Link
01/2018 - 10/2015
2Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2018 - 10/2015
2Lenalidomide (CC 5013)FDA Link
12/2017 - 07/2013
2Prednisolone (Predate)FDA LinkGeneric
12/2017 - 07/2013
2Prednisone (Sone)FDA LinkGeneric
10/2017 - 11/2015
2Bortezomib (Velcade)FDA Link
10/2017 - 11/2015
2Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
09/2013 - 01/2004
2Dasatinib (BMS 354825)FDA Link
05/2013 - 09/2009
2Messenger RNA (mRNA)IBA
08/2012 - 08/2012
2ribonucleotide polymeraseIBA
09/2009 - 09/2005
2Cyclosporine (Ciclosporin)FDA LinkGeneric
09/2007 - 02/2003
1Hydroxyurea (Hydrea)FDA LinkGeneric
12/2020
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2020
1Proto-Oncogene Proteins c-bcrIBA
01/2020
1NucleophosminIBA
02/2019
1Melphalan (Alkeran)FDA LinkGeneric
01/2019
1Biological ProductsIBA
04/2017
1ruxolitinibIBA
11/2015
1Leucovorin (Folinic Acid)FDA Link
10/2015
1Capecitabine (Xeloda)FDA Link
10/2015
1Fluorouracil (Carac)FDA LinkGeneric
10/2015
1Tacrolimus (Prograf)FDA LinkGeneric
10/2014
1HLA Antigens (Human Leukocyte Antigens)IBA
10/2014
1SteroidsIBA
10/2014
1Sirolimus (Rapamycin)FDA Link
10/2014
1ponatinibIBA
09/2014
1Circulating Tumor DNAIBA
09/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2013
1Proteins (Proteins, Gene)FDA Link
08/2012
1Neoplasm Antigens (Tumor Antigens)IBA
08/2012
1ibritumomab tiuxetan (Zevalin)FDA Link
09/2010
1Voriconazole (Vfend)FDA LinkGeneric
08/2010
1Capsules (Microcapsules)IBA
03/2007
1Tyrosine (L-Tyrosine)FDA Link
01/2004
1multidrug resistance-associated protein 1IBA
03/2003

Therapy/Procedure

20Therapeutics
10/2018 - 01/2004
14Cell Transplantation
01/2019 - 02/2003
6Stem Cell Transplantation
02/2019 - 08/2006
5Hematopoietic Stem Cell Transplantation
01/2019 - 05/2007
5Homologous Transplantation
01/2019 - 04/2009
4Transplantation
10/2014 - 01/2011
2Drug Therapy (Chemotherapy)
04/2017 - 01/2008
1Hematopoietic Stem Cell Mobilization
11/2015
1Combination Drug Therapy (Combination Chemotherapy)
10/2015
1Radioimmunotherapy
09/2010
1Maintenance Chemotherapy
11/2005